Copy Number Heterogeneity of JC Virus Standards

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Copy Number Heterogeneity of JC Virus Standards

Quantitative PCR is a diagnostic mainstay of clinical virology, and accurate quantitation of viral load among labs requires the use of international standards. However, the use of multiple passages of viral isolates to obtain sufficient material for international standards may result in genomic changes that complicate their use as quantitative standards. We performed next-generation sequencing ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2017

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.02337-16